Www.doh.dc.gov Cannabis, like all herbs, is a polypharmaceutical substance. 108 cannabinoids have been isolated (Hanuš 2008). The cannabis-derived cannabinoids of most therapeutic interest are. Lactobacillus acidophilus is a bacteria that exists naturally in the body, primarily in the intestines and the vagina. Lactobacillus acidophilus has been used as a probiotic, or 'friendly bacteria.' Lactobacillus acidophilus has been used in alternative medicine as a likely effective aid in treating diarrhea in children with rotavirus. Lactobacillus acidophilus has been used in alternative.
Pypendop, DrMedVet, DrVetSci, DACVAA, is a professor of veterinary anesthesiology at University of California, Davis. He earned his DVM and Doctor of Veterinary Science (PhD) degrees from University of Liege, Belgium, and completed a residency in anesthesia at University of California, Davis.
His research focuses on the clinical pharmacology of anesthetic and analgesic drugs, with an emphasis on cats. As part of this work, he has studied the pharmacokinetics and some effects of gabapentin. Its mechanism of action is not entirely clear but is likely related to inhibition of calcium and, possibly, sodium channels.
1. Gabapentin is excreted unchanged in humans but is metabolized to N-methyl-gabapentin in dogs. Results in faster elimination and ability for shorter dose intervals in dogs as compared with humans 2. The metabolism of gabapentin has not been studied in cats, but pharmacokinetics demonstrates faster elimination than in humans, with similar implications for dose intervals as in dogs. 3CLINICAL APPLICATIONSGabapentin has been used as an adjunct treatment for seizures in dogs and cats and as treatment for neuropathic pain.
Gabapentin may be effective as an adjunct treatment for acute pain in humans (eg, pain following some surgeries, including spinal surgery and hysterectomy) and, to a lesser extent, in dogs and cats. 10-16. However, meta-analyses of human studies have failed to show strong benefits.
17,18. A single case report described the successful use of gabapentin in the management of neuropathic pain in a horse. 19.
Most evidence showing efficacy of gabapentin in pain management in animals is anecdotal and not based on controlled studies.The recommended dose is variable, ranging from 10-20 mg/kg q8-12h in dogs 4,7-9,20 and 3-20 mg/kg q6-24h in cats.
By Chris Faubel, M.D.Topical administration of medications for pain management has become increasingly more common. Pharmaceutical companies are getting in the game with products such as Flector patches, Voltaren gel, Pennsaid topical solution, Lidoderm patches, and Qutenza patches. Numerous over-the-counter products also exist.Many patients need more than just one medication to treat their pain. And for some, the adverse effects and allergies of oral medications is too much to bear. For these patients, sometimes the best solution is having a compounding pharmacy put together a number of different medications with different mechanisms of action into a compounded cream that is applied directly over the site of pain.
I’ve been pleasantly surprised to find that Ketamine/Lidocaine and DMSO creams help with my widespread body pain a great deal. I suffer from fibromyalgia, but I originally got the creams for severe hernia pain, which they also help with. The K cream for me is at 10%, and the Lido is at 5%.I can’t handle taking oral pain meds beyond OTC ones because of the side-effects, and I’m thrilled to share the fact that there have been absolutely no side-effects at all with these creams.
In fact, there are no effects whatsoever except pain relief. And what a relief that is!This article was very helpful in my research to find the best ingredients to try for upcoming major surgery that I’ll be having.
I like that you gave the percentages for each med and explain how they work and why, and useful info like which ones are Na channel blockers, because I think that’s contraindicated for ME.Thank you! My foot & ankle specialist prescribed a compounded transdermal cream for nerve pain along the outside of my foot right below the ankle from toes to heels & it helps. I’m also been using it for fibromyalgia pain.
I recently tried it for varicose vein pain & have found it works for that too. Very pleased with results. I am diabetic so it also greatly helps with diabetic nerve pain in the feet. Very easy to use, mine comes in a clear plastic container that dispenses the right amount for each dose much like a lotion pump. Just need to rub it in well.
No mess, no pill. I think a physician has to place the order with the pharmacy. I’ve been prescribed a compounded lotion for inoperable severe lumbar spine degeneration with chronic low back pain from a decades-old injury. In recent years the back symptoms have worsened significantly after a total knee replacement that caused a leg-length discrepancy. That difference in leg length actually caused a slight scoliosis of the part of my spine with the severest arthritis, plus an anterior-rotational dislocation of the SI joint on top of the chronic back issues.So far I am very pleased with the results of my compound medicine as I refuse to take any opioids. This combined with CBD are a very good combination. I get the pain relief without any psychological effects with either, helping me remain fully functional in my profession.
I’m wondering if these types of medical marijuana products could also be added to the compounded lotion, mixed with the other meds. I get my compound lotion from a specialty pharmacy in Denver.The one problem with compounded medicines is very few insurance companies will cover them which makes absolutely no sense since the medications being compounded are generic drugs. The difference between what should be a $15 copay and nearly $400 non-covered price is ridiculous for a one-month supply.